

Announcements.

Looking to discover a little more about our client companies?
A selection of news and recent announcements can be found here.
FireAngel SafetyTech : Contract wins
RNS Number : 5868K FireAngel Safety Technology Group 17 December 2018 17 December 2018 FireAngel Safety Technology Group plc ("FireAngel" or the "Company") Contract wins FireAngel (AIM: FA.), one of Europe's leading developers and suppliers of home safety products, announces that it has secured agreements to……
RNS Number : 5868K
FireAngel Safety Technology Group
17 December 2018
17 December 2018
FireAngel Safety Technology Group plc
("FireAngel" or the "Company")
Contract wins
FireAngel (AIM: FA.), one of Europe's leading developers and suppliers of home safety products, announces that it has secured agreements to supply mains and battery-powered smoke and heat alarms to two housing associations in Scotland.
The Company will supply River Clyde Homes, a not-for-profit affordable housing provider with 5,800 homes, with a mix of mains and battery products. It has also signed a two-year agreement with Caledonia Housing Association, which owns and manages over 4,000 homes, to supply a mix of mains and Wi-Safe 2 battery alarms, which are all compatible with the Company's connected home solutions. This contract, along with the previously announced contract with Queens Cross Housing Association, has been secured through the Scottish Procurement for Housing framework.
Following changes to the Housing (Scotland) Act, expected to be enacted early in 2019, all homes in Scotland will require:
· sealed long-life battery or mains-wired alarms that are interlinked;
· one functioning smoke alarm in the room that is frequently used by the occupants in the daytime;
· one functioning smoke alarm in every circulation space on every floor;
· one heat alarm in every kitchen; and
· a carbon monoxide alarm will also need to be fitted in each room with a carbon-fuelled appliance or flue.
FireAngel's Wi-Safe 2 wireless interlink alarms ensure that each property achieves constant compliance through the use of interlinked alarms installed in the kitchen, hallway and living room. Additionally, FireAngel's unique monitoring platform, FireAngel Connect, allows for remote monitoring and instant notifications.
Neil Smith, Group Chief Executive of FireAngel, commented: "We are delighted to have signed two further contracts with housing associations in addition to our Queens Cross Housing Association agreement. Our alarms are designed to provide the highest level of protection at all times and to ensure compliance with the imminent new legislative changes requiring interlinked alarms in all properties. It is encouraging to see housing associations in Scotland recognising the imminent implementation of legislation and the need to ensure the products they are seeking to install are compliant with the upcoming regulations."
For further information, please contact:
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FireAngel Safety Technology Group plc |
02477 717 700 |
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Graham Whitworth, Executive Chairman |
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Neil Smith, Group Chief Executive |
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Stockdale Securities Limited |
020 7601 6100 |
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Tom Griffiths |
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Vigo Communications |
020 7390 0233 |
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Jeremy Garcia / Fiona Henson / Charlie Neish |
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Notes to Editors
About FireAngel Safety Technology Group plc ("FireAngel")
FireAngel's mission is to protect, save and improve our customers' lives by making innovative, leading edge technology simple and accessible. FireAngel is one of the market leaders in the European home safety products market and launched its own connected homes product proposition at the end of 2016.
FireAngel's principal products are smoke alarms, CO alarms and accessories. The Company has an extensive portfolio of patented intellectual property in Europe, the US and other selected territories. Products are sold under FireAngel's leading brands of FireAngel, FireAngel Pro, AngelEye and FireAngel Connect.
For further product information, please visit: www.fireangeltech.com
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseConcepta PLC : myLotus? successful UK launch
RNS Number : 6039K Concepta PLC 17 December 2018 17 December 2018 Concepta Plc ("Concepta" or the "Company") myLotus® successful UK launch Concepta Plc (AIM: CPT), the innovative UK healthcare company and developer of the proprietary self-test platform ("myLotus®") and suite of emerging test products targeting the mobile……
RNS Number : 6039K
Concepta PLC
17 December 2018
17 December 2018
Concepta Plc
("Concepta" or the "Company")
myLotus® successful UK launch
Concepta Plc (AIM: CPT), the innovative UK healthcare company and developer of the proprietary self-test platform ("myLotus®") and suite of emerging test products targeting the mobile health market is pleased to advise on the successful launch in the UK of its breakthrough myLotus® product for women's fertility.
myLotus® allows women to self-test to identify their optimal fertile days thereby improving their chances of naturally getting pregnant. myLotus® enables women to monitor their fertile phase as part of their menstrual cycle and is the only home test to 'quantitatively' measure personalised hormone levels and the 'rate-of-change' of these levels preceding ovulation to help aid a natural conception. Users measure, record and track their hormone levels and follow their fertility journey in an accompanying free downloadable app.
Whilst awareness, profile and sales of the myLotus® device are just commencing, feedback from early users and fertility bloggers has been very positive can be viewed online at www.myLotus.com
Discussions have also commenced with 'Key Opinion Leaders' to advise on the wider use of myLotus® especially for women who wish to carefully monitor their hormonal levels and for those who have previously struggled to conceive naturally, enabling an alternative for couples prior to considering more costly IVF treatment.
In addition to the growing myLotus® digital UK presence, the Company is preparing plans for the roll-out of myLotus® across Europe under its CE-mark approval. Commercial discussions have also commenced with retail providers to make myLotus® more broadly available across the UK.
Matthew Walls, Chairman said: "Although marketing and communications around myLotus® are just beginning, feedback from the early users has been exceptional. We will be raising awareness of the value of the myLotus® device and its window on fertility over the coming months via an increased online presence, Key Opinion Leaders and marketing of our initial fertility case studies. Further details can be viewed at www.myLotus.com."
Enquiries
Company: www.conceptaplc.com, Product: www.myLotus.com
Matthew Walls, Chairman
Tel: +44 (0) 1234 866601
SPARK Advisory Partners Limited (Nomad)
Neil Baldwin / Mark Brady
Tel: +44 (0)20 368 3550
Novum Securities
Colin Rowbury
+44 (0) 20 7399 9400
Yellow Jersey PR Limited (Financial PR)
Felicity Winkles Tel: +44 (0) 774 884 3871
About Concepta Plc:
Concepta Plc is an AIM-quoted pioneering UK healthcare company that has developed a proprietary product, myLotus®, targeted at the personalised mobile health market with a primary focus on increasing a woman's chances of getting pregnant naturally and for unexplained infertility in women.
myLotus® is currently the only consumer product which allows both quantitative and qualitative home (self-test) test measurement of a woman's personal luteinizing hormone (LH) during ovulation and human chorionic gonadotropin (hCG) hormone level during pregnancy, facilitating higher conception rates and early diagnosis of fertility issues. The proposition of myLotus® is to help women conceive naturally by identifying their window of fertility and optimal time for conception.
The Company has received CE-mark certification for myLotus® and has launched its first product in the UK. The Company is preparing plans to roll-out across the core EU countries in 2019.
myLotus® is expected to be beneficial to users who have been unable to conceive after 6 months of trying. This highly motivated target group of consumers won't typically be offered medical intervention until 12 months of unsuccessfully trying, with IVF typically not offered until two years. Research indicates couples start to take positive action ahead of this time with little medical support to help them do so.
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseXeros Tech Grp plc : MARKEN's position in US firefighter's PPE market
RNS Number : 5651K Xeros Technology Group plc 17 December 2018 RNS Reach 17 December 2018 Xeros Technology Group plc MARKEN establishes a unique position in US firefighter's personal protective equipment servicing market Xeros Technology Group plc (AIM: XSG, 'Xeros', 'the Group'), the developer and provider of……
RNS Number : 5651K
Xeros Technology Group plc
17 December 2018
RNS Reach
17 December 2018
Xeros Technology Group plc
MARKEN establishes a unique position in US firefighter's personal protective equipment servicing market
Xeros Technology Group plc (AIM: XSG, 'Xeros', 'the Group'), the developer and provider of water saving technologies with multiple commercial applications, today announces that MARKEN, its North American high performance workwear business specialising in the cleaning, inspection and repair of firefighter's personal protective equipment ('PPE'), has become the only Independent Service Provider ('ISP') in North America to secure UL DQS ISO ISO-9001 registration, recognising the company's highest standards of quality management.
The UL DQS ISO ISO-9001 registration has been secured for each of MARKEN'S sites in North America: North Las Vegas, Nevada; Austell, Georgia; Medley, Florida and Corona, California.
Additionally, MARKEN has become one of only a handful of ISPs to secure verification under both US National Fire Protection Association ('NFPA') 1851 and 1855 standards, covering structural, proximity and technical rescue PPE used by fire departments. The verifications allow MARKEN to clean, decontaminate, inspect and repair every element of a firefighter's PPE such as jackets, trousers, boots and helmets, using Xeros' unique, patented technologies.
Joey Beeman, General Manager of MARKEN commented:
"The welfare of the more than a million permanent and volunteer firefighters across the US is of paramount importance to us in developing MARKEN's service offering. With serious concerns about how firefighters are repeatedly exposed to dangerous situations and toxic carcinogens while in the line of duty, it's more important than ever to ensure their protective clothing and equipment is effectively cleaned, decontaminated and maintained to ensure it is kept in prime condition.
"Securing ISO registration recognises that MARKEN is driving up standards across the US market for the cleaning and maintenance of firefighter's clothing and specialist protective equipment.
"With both ISO and NFPA verification, MARKEN is rapidly establishing a reputation as the market leader in the US for the cleaning and maintenance of firefighter PPE.
"We are seeing considerable interest from fire departments across North America – acknowledging the clear benefits of MARKEN's higher standards of operation and Xeros' unique cleaning technologies in developing cost-effective and sustainable solutions for the cleaning and decontamination of firefighter PPE."
MARKEN is the only service provider operating in coast-to-coast locations in North America to hold UL DQS ISO 9001 registration and both UL NFPA 1851 and 1855 verification.
ENDS
Enquiries:
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Xeros Technology Group plc Mark Nichols, Chief Executive Officer Paul Denney, Chief Financial Officer
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Tel: 0114 321 6328
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Jefferies International Limited (Nominated Adviser and Joint Broker) Simon Hardy / Will Soutar
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Tel: 020 7029 8000 |
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Berenberg (Joint Broker) Chris Bowman / Ben Wright / Laure Fine
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Tel: 020 3207 7800 |
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Instinctif Partners Adrian Duffield / Kay Larsen/ Chantal Woolcock
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Tel: 020 7457 2020 |
Notes to Editors
Xeros Technology Group plc (LN: XSG) is a platform technology company that is reinventing water intensive industrial and commercial processes.
Xeros' uses its patented XOrbTM technologies to significantly reduce the amount of water used in a number of major applications with the remaining water becoming far more efficient in either affixing or removing molecules from substrates such as fabrics and garments. The result being significant improvements in economic, operational and sustainability outcomes.
Xeros has three divisions working in the garment finishing (Textile Technologies), tanning (Tanning Technologies, branded Qualus) and cleaning/laundry (Cleaning Technologies) markets. In cleaning/laundry, the company has three applications covering domestic laundry, commercial laundry (branded "Hydrofinity") and the cleaning of high performance workwear (branded "Marken").
For more information, please visit – http://www.xerostech.com/
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseIntegumen PLC : Labskin-On-A-Chip
RNS Number : 3171K Integumen PLC 13 December 2018 13 December 2018 Integumen plc ("Integumen" or "the Company") Labskin-On-A-Chip to monitor real-time skin related diseases and Labskin-AI data analysis to predict the best course of treatment Integumen is pleased to announce a cross-platform biophysics agreement with AI……
RNS Number : 3171K
Integumen PLC
13 December 2018
13 December 2018
Integumen plc
("Integumen" or "the Company")
Labskin-On-A-Chip to monitor real-time skin related diseases and Labskin-AI data analysis to predict the best course of treatment
Integumen is pleased to announce a cross-platform biophysics agreement with AI developer, Rinocloud Limited, in association with Cork Institute of Technology's Nimbus embedded systems research institute and its Cappa Photonics Laboratory to develop Labskin-On-A-Chip ("LOAC") technology.
Labskin-On-A-Chip (LOAC)
Pioneering animal free, clinical research skin-treatment test platform by exploiting Photonics. Labskin is grown on a microchip where light is generated, detected and manipulated, using the cutting-edge use of lasers and fibre-optics on an electro-optical device.
Labskin is already a valuable tool for our pharma and skin care clients:
· Laboratory grown human skin used for testing of skin products and treatments,
· Can be populated with harmful viruses,
· Tested using natural skin conditions with good and bad bacteria from patients.
LOAC real-time and hands-free can monitor:
· Bacteria and virus growth or decline on Labskin – human skin,
· Balance of good and bad bacteria during skin treatments,
· The impact on the skin's microflora of skin care products and treatments.
RinoLab AI Software:
Combined with the RinoLab/Labskin AI software tools, analysis of the data via Labskin AI client portal can be fed into pharmacodynamic in-silico (pharmaco-dynamic/pharmaco-kinetic) models and used in the pharmaceutical clinical research sector. For clinical research the long-term data accumulated will provide clinical data for new products and skin treatments.
World first in skin treatment clinical research.
Labskin-on-a-Chip as a pre-clinical and post-clinical platform is a major step up for all skin related disease treatments. The completion of the project over the next 12 months is expected to provide every dermatology clinic with a desktop ability to take a swab of the patient's own bacteria, place it on the Labskin and provide the best course of treatment.
Fin Murray CEO of Rinocloud commented:
"This is an exciting cross platform development in artificial intelligence at Rinolab and Rinocloud. Our collaboration with Labskin for the AI platform and our work with educational institutions who use Rinocloud has opened up a major opportunity that is set to transform the lives of 3% of the population who suffer daily from skin diseases."
Gerard Brandon CEO of Integumen commented:
"Right time, right place, right people, right technology and the right thing to do. In the short time we have been working with the team at Rinocloud we have identified many synergies that bringing together biology, physics, software and most importantly a can-do attitude. I look forward to working closely with the team to rolling this out in late 2019."
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Integumen plc |
Gerard Brandon, CEO
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+44 (0) 122 392 6660 |
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SPARK Advisory Partners Limited (Nominated Adviser)
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Neil Baldwin/Andrew Emmott |
+44 (0) 113 370 8974 |
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Hybridan LLP (Broker) |
Claire Noyce |
+44 (0) 20 3764 2341 |
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseXeros Tech Grp plc : Xeros completes outsourcing of Hydrofinity
RNS Number : 1700K Xeros Technology Group plc 12 December 2018 RNS Reach 12 December 2018 Xeros Technology Group plc Xeros completes outsourcing of Hydrofinity servicing in US Xeros Technology Group plc (AIM: XSG, 'Xeros', 'the Group'), the developer and provider of water saving technologies with multiple……
RNS Number : 1700K
Xeros Technology Group plc
12 December 2018
RNS Reach
12 December 2018
Xeros Technology Group plc
Xeros completes outsourcing of Hydrofinity servicing in US
Xeros Technology Group plc (AIM: XSG, 'Xeros', 'the Group'), the developer and provider of water saving technologies with multiple commercial applications, has completed the transfer of servicing of Xeros' commercial laundry customers, across the whole of the US, with the signing of a series of regional agreements with full-service distributors. The Group's commercial laundry business is branded Hydrofinity.
As previously announced in November with the signing of the first agreement with ELS, these regional distributors will now service all Hydrofinity's existing and future customers in the US with significant savings accruing to Xeros. These distributors will continue to stock and sell Xeros commercial washing machines.
Agreements have recently been signed with organisations such as Viking Services to cover California and Consolidated Laundry Equipment Inc to cover the mid-Atlantic region of the US, extending the sales and service coverage of Hydrofinity.
This agreement reflects the Hydrofinity strategy to reduce its physical presence in the US market and to move to a licensing model. This model has already been rolled-out in international markets with agreements in place in South Africa, UAE, Australia and China.
Mark Nichols, Chief Executive of Xeros, said:
"These agreements in the US follow similar agreements recently signed covering China, Dubai and South Africa. They will enable our Hydrofinity business to increase revenues from a lower cost base whilst continuing to provide customers with excellent service."
Enquiries:
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Xeros Technology Group plc Mark Nichols, Chief Executive Officer Paul Denney, Chief Financial Officer
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Tel: 0114 321 6328
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Jefferies International Limited (Nominated Adviser and Joint Broker) Simon Hardy / Will Soutar
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Tel: 020 7029 8000 |
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Berenberg (Joint Broker) Chris Bowman / Ben Wright / Laure Fine
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Tel: 020 3207 7800 |
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Instinctif Partners (Financial PR) Adrian Duffield / Kay Larsen / Chantal Woolcock |
Tel: 020 7457 2020 |
Notes to Editors
Xeros Technology Group plc (LN: XSG) is a platform technology company that is reinventing water intensive industrial and commercial processes.
Xeros' uses its patented XOrbTM technologies to significantly reduce the amount of water used in a number of major applications with the remaining water becoming far more efficient in either affixing or removing molecules from substrates such as fabrics and garments. The result being significant improvements in economic, operational and sustainability outcomes.
Xeros has three divisions working in the garment finishing (Textile Technologies), tanning (Tanning Technologies, branded Qualus) and cleaning/laundry (Cleaning Technologies) markets. In cleaning/laundry, the company has three applications covering domestic laundry, commercial laundry (branded "Hydrofinity") and the cleaning of high performance workwear (branded "Marken").
For more information, please visit – http://www.xerostech.com/
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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Closee-Therapeutics plc : Research Collaboration Agreement with Novo Nordisk
RNS Number : 8912J e-Therapeutics plc 10 December 2018 E-therapeutics Signs Research Collaboration Agreement with Novo Nordisk Oxford, UK, 10 December 2018: e-therapeutics plc (AIM: ETX, "e-therapeutics") is pleased to announce a research collaboration with Novo Nordisk under which the companies will use e-therapeutics' proprietary Network-Driven Drug……
RNS Number : 8912J
e-Therapeutics plc
10 December 2018
E-therapeutics Signs Research Collaboration Agreement with Novo Nordisk
Oxford, UK, 10 December 2018: e-therapeutics plc (AIM: ETX, "e-therapeutics") is pleased to announce a research collaboration with Novo Nordisk under which the companies will use e-therapeutics' proprietary Network-Driven Drug Discovery (NDD) platform to look to discover potentially novel biological mechanisms and therapeutic approaches for a specific area of type-2 diabetes.
Type 2 diabetes currently accounts for approximately 90% of the estimated 425 million people with diabetes globally[1], and new treatments are urgently required to tackle the growing incidence of the condition.
Under the Agreement, e-therapeutics will work with Novo Nordisk over a period of 12 months and use its NDD approach to identify novel intervention strategies, biological pathways and compounds for testing that could potentially form the basis of novel therapies.
Jan Nygaard Jensen, Deputy Head of Novo Nordisk Research Center Oxford and Head of Bioinformatics, said: "We are looking forward to cooperating with e-therapeutics. It is an exciting technology and we will investigate if it can support some of the early target discovery efforts we are building in Novo Nordisk Research Center Oxford".
e-therapeutics will be reimbursed for its work under this collaboration and Novo Nordisk has the option to license relevant IP generated under the collaboration. Any future license would require mutual agreement of commercial terms. Financial details of the collaboration have not been disclosed.
Dr Ray Barlow, CEO at e-therapeutics, said: "We are delighted to be working with Novo Nordisk, a world leader and innovator in diabetes care. This collaboration highlights the use of our Network-Driven Drug Discovery (NDD) platform to understand and potentially create new treatments for complex diseases of great relevance to society, medicine and the industry. Our new collaboration with Novo Nordisk is the result of a systematic and rigorous business development exercise over the past year and we hope to announce a number of additional collaborations during the course of 2019."
ENDS
For more information, please contact:
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e-therapeutics plc Ray Barlow, Chief Executive Officer Steve Medlicott, Finance Director
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Tel: +44 (0)1993 883 125
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Numis Securities Limited Michael Meade/Freddie Barnfield (Nominated Adviser) James Black (Corporate Broking)
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Tel: +44 (0) 207 260 1000
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FTI Consulting Simon Conway/Brett Pollard |
Tel: +44 (0) 203 727 1000 |
About e-therapeutics
We are an Oxford, UK-based company with a unique and powerful computer-based drug discovery platform and a specialised approach to network biology.
Our novel network-driven methodology allows us to discover new and better drugs in a more efficient and effective way.
We use our highly productive drug Discovery Engine to develop our own IP-protected, pre-clinical drug discovery programmes which will be of interest to partners looking to acquire or in-license novel and differentiated assets. We are currently developing two programmes in immuno-oncology and have a number of partner-ready projects in areas such as fibrosis and tumour microenvironment.
Because of our novel network-driven drug discovery (NDD) approach, we believe there is potential to enter into several different types of collaborative partnerships with biotech, pharma and other technology companies to create sustainable mutual value.
About Network-Driven Drug Discovery (NDD)
e-Therapeutics' proprietary NDD platform comprises a suite of powerful computational tools to augment and interrogate the vast amount of biological information currently available in both public and private databases.
Our NDD platform is founded on sophisticated network science and employs techniques such as machine learning, artificial intelligence (AI) and state-of-the-art data analysis tools. Using our biological expertise, we can create and analyse network models of disease to identify likely proteins that could effectively be disrupted to treat the disease.
We believe that our network-driven approach more realistically reflects the true complexity of disease, with its multiple and often interconnected cellular pathways. By modelling and analysing disease networks and considering the pattern of connections between proteins, and not just single pathways, we more efficiently select the very best drug-like compounds for screening and for subsequent medicinal chemistry and pre-clinical testing. With our novel methodology, significant numbers of active molecules can be identified and tested quickly. Our approach is highly productive and consistently generates hits that have been progressed into potent, selective and novel drug molecules.
Our overall aim is to discover more efficacious drugs more effectively. By using more biologically realistic, cell and tissue-based assays we can choose and design compounds that are more likely to translate into better, more clinically efficacious drugs.
[1] IDF Diabetes Atlas, 8th Edition (2017)
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseValiRx PLC : Update on VAL201 Clinical Trial
RNS Number : 8910J ValiRx PLC 09 December 2018 VALIRX PLC ("ValiRx" or the "Company") UPDATE ON VAL201 CLINICAL TRIAL "Positive Effect on Cancer Patients" "Evidence revealed of decrease in prostate cancer biomarker PSA, related to dosing with VAL201" London, UK., 10 December 2018: ValiRx Plc……
RNS Number : 8910J
ValiRx PLC
09 December 2018
VALIRX PLC
("ValiRx" or the "Company")
UPDATE ON VAL201 CLINICAL TRIAL
"Positive Effect on Cancer Patients"
"Evidence revealed of decrease in prostate cancer biomarker PSA, related to dosing with VAL201"
London, UK., 10 December 2018: ValiRx Plc (AIM: VAL), the clinical stage biotechnology company, is proud to announce that independent analysis of VAL201 data shows a statistically significant dose dependant response in the reduction of PSA correlated to time on the Phase l/ll clinical trial, involving patients with hormone-sensitive and hormone-resistant prostate cancer.
This represents an initial formal statistical analysis of the VAL201 clinical data conducted by Dr Wilson Caparrós-Wanderley, an independent statistical consultant. This was undertaken using a non-parametric approach – both the well-established 'Friedman Test' (developed by M. Friedman in 1937) and the most up-to-date statistical method, 'Repeated Measures Multiple Correlation Analysis' (refined by Bakdash and Marusich in 2017).
This analysis reveals that volunteers treated with VAL201 display a statistically significant correlation for reductions over time in the amount of Testosterone and Prostate Specific Antigen ("PSA"), both of which are commonly-used markers for disease progression in prostate cancer.
The data further confirms that VAL201 has no statistically significant adverse trends across liver or kidney function. Furthermore, with no impact on cardiac rhythm in the patients either, this data further reinforces the continuation of the good safety and tolerability data emerging from the trial.
In addition to the independent analysis, the pharmacokinetics information collected from the clinical evaluation of ValiRx's more recent patients, shows that ValiRx is addressing the protocol's primary and secondary endpoints – as well as all the exploratory tertiary end points.
Further information about the endpoints is to be found posted on the NIH website, www.ClinicalTrials.gov, under: 'Dose Finding Safety Study of VAL201 in Cancer Patients (VAL201-001)'.
Dr Satu Vainikka, CEO of ValiRx, commented: "I am delighted to receive this analysis from an external expert, showing that VAL201 is having a positive and desired effect on prostate cancer patients' disease markers. Effectively, the more a patient takes VAL201, the more a patient's PSA will decrease".
"This is fantastic news and it heralds our entry into the pivotal stage of VAL201's clinical trial programme. I thank the team for their hard work in delivering these very encouraging and positive outcomes".
This announcement contains inside information for the purposes of Article 7 of EU Regulation 596/2014.
*** ENDS ***
For more information, please contact:
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ValiRx plc |
Tel: +44 (0) 20 3008 4416 |
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Dr Satu Vainikka, Chief Executive |
Tel: +44 (0) 20 3008 4416 |
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Tarquin Edwards, Head of Communications. |
Tel: +44 (0) 7879 458 364 |
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Cairn Financial Advisers LLP (Nominated Adviser) Liam Murray/Jo Turner/Richard Nash |
Tel: +44 (0) 20 7213 0880 |
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Novum Securities Limited (Broker) Colin Rowbury |
Tel: +44 (0) 20 7399 9400 |
Notes for Editors
About ValiRx
ValiRx is a biotechnology oncology focused company specialising in developing novel treatments for cancer and associated biomarkers. It aims to make a significant contribution in "precision" medicine and science, namely to engineer a breakthrough into human health and well-being, through the early detection of cancer and its therapeutic intervention.
The Company's business model focuses on out-licensing therapeutic candidates early in the development process. By aiming for early-stage value creation, the company reduces risk considerably while increasing the potential for realising value. The group is already in licensing discussions with major players in the oncology field.
ValiRx's two classes of drugs in development, which each have the potential for meeting hitherto unmet medical needs by existing methods, have worldwide patent filings and agreed commercial rights. They originate or derive from World class institutions, such as Cancer Research UK and Imperial College.
Until recently, cancer treatments relied on non-specific agents, such as chemotherapy. With the development of target-based agents, primed to attack cancer cells only, less toxic and more effective treatments are now possible. New drugs in this group-such as those in ValiRx's pipeline-promise to greatly improve outcomes for cancer patients.
The Company listed on the AIM Market of the London Stock Exchange in October 2006 and trades under the ticker symbol: VAL
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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CloseBiome Technologies : Grant funding from Innovate UK
RNS Number : 5952J Biome Technologies PLC 06 December 2018 6 December 2018 Biome Technologies plc ("Biome", "the Company" or "the Group") Biome Technologies plc, the leading bioplastics and radio frequency technology business, is pleased to announce that it has been awarded a further……
RNS Number : 5952J
Biome Technologies PLC
06 December 2018
6 December 2018
Biome Technologies plc
("Biome", "the Company" or "the Group")
Biome Technologies plc, the leading bioplastics and radio frequency technology business, is pleased to announce that it has been awarded a further £0.6 million of grant funding from Innovate UK to support a project focused on pilot-scale production of a novel bioplastic building block.
Over the last five years, Biome Technologies has led a £6 million development programme to bring a range of novel highly functional bio-based and biodegradable polymers to market using industrial biotechnology techniques. This programme currently involves seven universities, some 25 scientists and engineers and other partners.
Earlier in 2018, the Company reported that the technical feasibility of a number of these potential polymers had been ascertained and that work was now to be focused on establishing the viability of production and commercial scale-up. Following extensive techno-economic analysis this project, one of three key elements of our work in this area, will focus on the scale-up of of PDCA (2,5-pyridinedicarboxylic acid) from bio-based intermediates that can be obtained from the lignin breakdown pathway.
This two-year, £0.8 million project in collaboration with the University of Nottingham will use a robust, metabolically diverse organism (Cupriavidus necator) in a contained environment to produce PDCA at pilot-scale. The work uses advanced synthetic biology techniques and state-of-the-art processing for the eventual production of highly biodegradable, compostable and recyclable bioplastic polymers suitable for flexible packaging applications.
Biome Technologies CEO Paul Mines commented:
"The UK government has set a target of eliminating all avoidable plastic waste by 2042. Bioplastics will play a crucial role in achieving this target by reducing waste. However, current bioplastic technology is limited by price and performance in some applications. Our development programme is intended to change that position by preparing a new generation of polymers with improved functionality."
The funding, provided by UK Research and Innovation and delivered by Innovate UK, was awarded as part of a £20 million Open Competition to deliver game changing or disruptive innovations with significant potential for impact on the UK economy.
The UK Government's Industrial Strategy sets out 4 Grand Challenges, including Clean Growth, to put the UK at the forefront of the industries of the future. Exemplifying the focus on renewable materials, on 5 December 2018, up to £60 million of new public funding was announced for the Smart Sustainable Plastic Packaging Challenge, through the Industrial Strategy Challenge fund. Illustrating economic potential of such products, a recent report by bioeconomy consultants NNFCC found that plastics made from plants instead of oil, many of which are biodegradable – could create 34,000 jobs and contribute £1.92 billion to the UK economy in the next decade.
More information about the Group's work in this area can be found at www.biomebioplastics.com/industrial-biotechnology.
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For further information please contact: Biome Technologies plc |
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Paul Mines, Chief Executive Officer |
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Declan Brown, Group Finance Director |
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www.biometechnologiesplc.com |
Tel: +44 (0) 2380 867 100 |
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Allenby Capital |
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David Hart/Alex Brearley (Nominated Adviser) Kelly Gardiner (Broker) |
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www.allenbycapital.com |
Tel: +44 (0) 20 3328 5656 |
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About Biome
Biome Technologies plc is an AIM listed, growth-orientated, commercially driven technology group. Our strategy is founded on building market-leading positions based on patented technology and serving international customers in valuable market sectors. We have chosen to do this by developing products in application areas where the value-added pricing can be justified and that are not reliant on government legislation. These products are driven by customer requirements and are compatible with existing manufacturing processes. They are market rather than technology-led.
The Group comprises two divisions, Biome Bioplastics Limited and Stanelco RF Technologies Limited. Biome Bioplastics is a leading developer of highly-functional, bio-based and biodegradable plastics. The company's mission is to produce bioplastics that challenge the dominance of oil-based polymers. Stanelco RF Technologies designs, builds and services advanced radio frequency (RF) systems. Dielectric and induction heating products are at the core of a product offering that ranges from portable sealing devices to large furnaces for the fibre optics markets.
In 2018, the Board has adopted the following three high level KPIs for the next three years to continue its ambitious momentum:
· Compound revenue growth of 25% per annum across the Group and 40% compound revenue growth in the Bioplastics division
· Diversify the Group's turnover by product and market to ensure that no one product or end customer contributes more than 15% of revenues by 2020
· Increase investment in the Group's next generation of products by spending significantly more per annum on average than the £0.3m per annum average spend over the previous strategic objective cycle
www.biomebioplastics.com and www.thinkbioplastic.com
www.stanelcorftechnologies.com
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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NRAEAPASEEEPFFF
CloseBidstack Group PLC : Contract with Codemasters
RNS Number : 5986J Bidstack Group PLC 06 December 2018 Certain information contained within this Announcement is deemed by the Company to constitute inside information as stipulated under the Market Abuse Regulation (EU) No. 596/2014 ("MAR"). Upon publication of this Announcement, this information is now considered to be in……
RNS Number : 5986J
Bidstack Group PLC
06 December 2018
Certain information contained within this Announcement is deemed by the Company to constitute inside information as stipulated under the Market Abuse Regulation (EU) No. 596/2014 ("MAR"). Upon publication of this Announcement, this information is now considered to be in the public domain.
6 December 2018
Bidstack Group PLC ("Bidstack or "the Company")
Contract with Codemasters
Bidstack Group plc (AIM: BIDS.L), the native in-game advertising group, is pleased to announce that it has signed a contract with Codemasters, the AIM listed award-winning video game developer and publisher, to provide native in-game advertising within two of Codemasters' titles, beginning with DiRT Rally 2.0, the sequel to the successful BAFTA nominated DiRT Rally.
Bidstack will provide native in-game advertising that will enable brands to reach a unique gaming audience through some of the most recognised racing franchises in the world.
The three-year exclusive contract positions Bidstack to manage the virtual advertising real estate for Codemasters across multiple platforms.
According to Codemasters, Dirt Rally 2.0 will launch on the PlayStation®4 computer entertainment system and the Xbox One family of devices including the Xbox One X and Windows PC, on Tuesday 26th February 2019.
James Draper, CEO, said, "Our agreement with Codemasters, a AAA rated games developer, provides us with further evidence that our proprietary technology is relevant and in demand by the world's leading games creators."
Frank Sagnier, CEO of Codemasters, commented, "We've been impressed by both the technology and brand reach of the Bidstack team. Most importantly they understand the importance of the quality of our assets and the need to deliver a solution that appeals to both brands and our loyal gamers. We look forward to working with them."
Contacts
Bidstack Group PLC
James Draper, CEO via Alma PR
Spark Advisory Partners
Mark Brady/Neil Baldwin/James Keeshan +44 (0) 203 368 3550
Peterhouse Capital Limited
Eran Zucker/Lucy Williams/Duncan Vasey +44 (0) 20 7409 0930
Alma PR
Josh Royston/ Sam Modlin +44 (0) 203 405 0205
Notes to editors
Bidstack is an advertising technology company which provides dynamic, targeted and automated native in-game advertising for the global video games industry across multiple platforms. Its proprietary technology is capable of inserting adverts into natural advertising space within video games across multiple video games platforms (mobile, PC and console).
Bidstack's customers are games publishers and developers (on the supply side), and advertising agencies, brands and programmatic advertising platforms (on the demand side). Bidstack contracts exclusive access to the native in-game advertising space within video games from their developers or publishers and sells that advertising space either direct to specific brands and their agencies or through programmatic advertising platforms.
About DiRT
The first game in Codemasters' fully owned "DiRT" franchise was launched in 1998 as "Colin McRae Rally". This was broadened from pure rally car racing to off-road racing including buggies and trucks, with the launch of the rebranded "DiRT" in 2007. Critics and consumers consider "DiRT" to be one of the best off-road racing franchises in the industry. "DiRT", "DiRT 2", "DiRT 3" and "DiRT Rally" all earned BAFTA nominations, and "DiRT Rally" and "DiRT 4" are tied as the second highest rated racing games on PS4 across all racing categories (85 per cent. Metacritic).
"DiRT 4", the most recent release in this franchise, was also awarded 2017 Racing Game of the Year by Game Informer, a leading US games publication. The franchise has in excess of 450,000 fans on Facebook and over 400,000 monthly active gamers.
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
END
CNTFSAFUIFASELE
ClosePanoply Holdings PLC : Admission to AIM and first day of dealings
RNS Number : 3028J Panoply Holdings PLC (The) 04 December 2018 4 December 2018 The Panoply Holdings PLC ("The Panoply" or the "Company") Admission to AIM and first day of dealings Oversubscribed fundraise of £5.4m The Panoply Holdings PLC, a digitally native technology services company, is……
RNS Number : 3028J
Panoply Holdings PLC (The)
04 December 2018
4 December 2018
The Panoply Holdings PLC
("The Panoply" or the "Company")
Admission to AIM and first day of dealings
Oversubscribed fundraise of £5.4m
The Panoply Holdings PLC, a digitally native technology services company, is pleased to announce that admission of its shares to trading on the AIM market of the London Stock Exchange ("Admission") will take place and dealings will commence at 8.00 a.m. today under the ticker TPX and the ISIN GB00BGGK0V60.
The Company successfully raised gross proceeds of £5.0m, before expenses, through an oversubscribed placing of 6,756,755 new Ordinary Shares at 74 pence per Ordinary Share (the "Placing Price") together with a vendor sale of an additional 526,615 Ordinary Shares at the Placing Price raising a further £400k for the vendor. Based on the Placing Price, the market capitalisation of the Company at Admission is approximately £30 million. Following admission, the Company will have 40,601,642 Ordinary Shares in issue.
Stifel is acting as the nominated adviser and sole broker to the Company. The Panoply is EIS/VCT-qualifying, profitable, debt-free, and plans to pay a dividend from 2020.
The Panoply was founded in 2016 with the aim of identifying and acquiring best-of-breed specialist information technology and innovation consulting businesses across Europe, to form regional clusters of group companies positioned to deliver services that help clients digitally transform their businesses for the automation age. From Admission, the four companies below will become part of the enlarged group (the "Enlarged Group" or "The Panoply Group"):
• Bene Agere: an Oslo-based strategy and management consultancy;
• Manifesto Digital: an award-winning London-based digital experience agency;
• Notbinary: an award-winning London-based IT consultancy focused on digital transformation; and
• Questers: an award-winning provider of onshore and nearshore agile software development services
Each of these four businesses is independently profitable and has a strong order backlog that supports their organic growth.
The four businesses service a breadth of blue-chip customers between them, including Unilever, BBC, National Trust, Unicef UK, Kew Gardens, DVLA, London Southbank University, Funding Circle and Shelter.
Key strengths
Significant market opportunity
Independent research house, International Data Corporation (IDC), estimates that the market for digital transformation services in EMEA will rise from $45 billion in 2017 to $82 billion by 2021.
Group platform
The Panoply provides a platform for companies which join the Group to accelerate their organic growth through cross-selling, as well as by leveraging The Panoply brand, network, listed status and balance sheet.
Alignment of interests
The Panoply's acquisition formula involves a significant proportion of the consideration for each acquisition being issued in Ordinary Shares, thereby ensuring alignment of interests of the target companies' selling shareholders with the existing shareholders.
Decentralised operating model
The Panoply's operating model allows companies within the Panoply Group to continue to remain entrepreneurial and creative, unstifled by bureaucracy:
– Central control is provided by a non-executive director, appointed by the Board of the Company to the board of each Panoply Group company, to provide governance, as well as guidance and oversight on growth strategy and collaboration with other Panoply Group Companies;
– The aim of this model is to provide clients with better outcomes, faster execution and lower cost for higher quality work.
Profitable and cash-generative
At Admission, the Enlarged Group is profitable, cash generative, debt-free and only intends to make accretive acquisitions going-forward.
Focused growth strategy
– The Panoply's Acquisition Formula is designed to attract ambitious companies, confident in their ability to grow profitably, while rewarding cross-selling and collaboration;
– The Panoply's management has an extensive network to help identify, attract and execute future acquisitions.
Experienced Management and Board with proven track record
The Panoply is managed by highly experienced executive and non-executive directors combining strong sector, public company and international mergers and acquisitions expertise with a track record of building, growing and exiting services companies.
Neal Gandhi, Chief Executive Officer, commented:
"The Panoply is a services company assembled to meet the demands created by the "fourth industrial revolution", combining the very best talent to service the growing technical needs of clients with innovation, creativity and efficiency. With digital transformation becoming more and more critical to companies' success across many verticals, this is the right time for a digitally native business such as ours to come to the market and capitalise on that structural shift. The old consultancy model is dying, and our decentralised, agile operating model is here to take its place.
"We have ambitious growth plans and are confident that AIM will be the right platform to support us in rapidly scaling the business. Admission to the exchange will bolster our brand and provide the capital necessary to pursue further, sustainable growth."
The Company's Admission Document can be found at: www.thepanoply.com
Enquiries:
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About The Panoply
The Panoply is a digitally native technology services company, built to service clients' digital transformation needs. Founded in 2016, with the aim of identifying and acquiring best-of-breed specialist information technology and innovation consulting businesses across Europe, the Group collaborates with its clients to deliver the technology outcomes they're looking for at the pace that they expect and demand.
www.thepanoply.com
Strategy
The Directors believe that the key to the future success of The Panoply Group is through a combination of an organic and acquisitive growth strategy.
The Panoply Group's primary strategy is to acquire companies in order to build regional clusters of complementary companies across Europe and support them in achieving faster organic growth, by allowing them to upsell, cross-sell and therefore win bigger deals.
The Directors believe that The Panoply's formulaic acquisition process will enable the Panoply Group to complete acquisitions quickly and cost effectively:
1. The Panoply identifies target companies that are primarily service-based, with annual revenues of up to £10 million. Target companies should be profitable, with limited or no debt, and most importantly, show potential for clear sales synergies with the Enlarged Group;
2. The Panoply carries out a due diligence process, drawing on the experience of its Directors and wider management and advisory teams. External professional advisors are used as required; and
3. once a potential target has been identified and the due diligence process completed to The Panoply's satisfaction, a price is agreed with the relevant business vendors based on a defined consideration formula. Under this formula the price is determined by reference to a multiple of the target's last 12 months EBITDA. Additional consideration may then become payable based on the target's ability to meet performance targets over the following 24 months, one of the parameters being cross sales within The Enlarged Group. The Panoply's Consideration Formula contains a clawback mechanism with a view to providing the Company with downside protection in the event that a target company's profit falls in the two years following acquisition.
In the short to medium term, the majority of the consideration payable in respect of the acquisition of target companies is expected to be satisfied by the issue and allotment of Ordinary Shares. The Directors intend that each acquisition agreement will include customary lock-in undertakings in respect of any Ordinary Shares issued.
The Directors believe that The Panoply's model will be attractive to target companies on account of its:
Listed status
Admission will provide The Panoply with a profile that all The Panoply Group companies can use to leverage in new business opportunities. Indeed, smaller IT services companies come across customer procurement hurdles that may be removed once companies join The Panoply Group. In addition, Admission provides a platform for The Panoply to make further acquisitions, as well as access to capital, which can be used to help facilitate further organic growth;
Operating model
The Panoply's operating model is to allow companies to continue to operate largely autonomously. This allows the existing entrepreneurs of target companies to continue to run their companies much like they did prior to acquisition. In order to provide additional support and guidance to management teams, as well as ensuring timely information and reporting flows back to The Panoply board, The Panoply provides each of its subsidiaries with a non-executive director, who sits on its board;
Cross selling and leverage opportunities
The Panoply's strategy is to acquire companies within specific geographic locations, in order to create regional clusters of companies in each jurisdiction. Each company acquired in a specific geographical location will have little or no service crossover with other companies within its own geographical regional cluster. The Panoply will seek to acquire complementary companies rather than competing companies and then seek to leverage the cross selling opportunities amongst them;
Marketing strategy
The Panoply's marketing strategy is to provide additional awareness for all of The Panoply Group companies, carrying out activities to a much larger scale than each Panoply Group company would be able to achieve individually. Each Panoply Group company will be rebranded by the addition of the TPX prefix to its name in order to better signpost to clients the breadth of the offering and facilitate cross-selling; and
Ability to attract and retain high quality staff
The Panoply Group structure is designed to attract talent at all levels of seniority. The Directors believe that The Panoply's model will be attractive as it is designed to enable a target company and its employees to take advantage of the benefits of being part of a larger group whilst at the same time still retaining a significant level of autonomy. Admission itself provides the opportunity to attract and incentivise high-quality staff through equity incentives that are more realisable than in private companies.
Reasons for Admission and use of proceeds
The Directors believe that Admission will be an important step in the Enlarged Group's development, as well as providing the Company with the net proceeds of the placing. It is the view of the Directors that Admission will:
• enhance the perceived credentials of the Enlarged Group with existing and potential customers/clients;
• allow the Enlarged Group to access equity capital effectively in order to provide the Company with the financial flexibility to pursue further growth opportunities;
• help the Enlarged Group attract and retain high-quality and/or key staff; and
• provide the Company with the flexibility to use its shares as currency for acquisition opportunities.
Use of proceeds
The Directors intend to use the net proceeds of the Placing principally to provide further investment into The Panoply Group companies and for working capital purposes.
Dividend policy
The Directors recognise the importance of dividend income to Shareholders and, subject to the availability of distributable reserves, the retention of funds required to finance the future growth of the Enlarged Group and such other factors which the Directors may from time to time deem relevant, anticipate paying a regular dividend (if appropriate). The Directors' current intention is to recommend the commencement of dividend payments after the finalisation of the Company's final accounts for the 30 financial year ended 31 March 2020. There can be no assurance as to whether dividend distributions will occur as intended, the amount of dividend payments or the timing of any such payment.
High quality board
Executive Directors
Neal Narendra Gandhi, aged 51, Co-Founder and Chief Executive Officer
Neal is a serial tech entrepreneur having co-founded four companies that exited successfully with a combined value of £117m. He co-founded his first company at the age of 21 and, under the brand name of Jungle.com, that company went on to be sold to GUS for £37m. In 1996 he co-founded Xplora and sold it to Nasdaq-listed USWeb in 1998. Neal then co-founded Attenda, a managed services consultancy which went on to be sold for £72m; one part to Telecity Plc and the other to Darwin Private Equity. In 2006 he founded QuickStart Global, an off-shore IT service provider, which grew rapidly, and in 2010 was listed in the Sunday Times Tech-Track 100 at number 3, his second company in that list with Attenda having been listed at number 2 in 2001.
Oliver James Rigby, aged 37, Co-Founder and Chief Financial Officer
Oliver qualified as an accountant with MRI Moores Rowland LLP in 2006 before spending six years as an adviser in corporate finance with Daniel Stewart and Deloitte. Oliver acted as a Nominated Adviser to the AIM Market of the London Stock Exchange and was one of their youngest Qualified Executives. Prior to co-founding The Panoply, Oliver set up Growth Company FD Limited in 2012 to provide part- time CFO and corporate finance support to growing businesses. He has worked with clients across a range of sectors and sizes including AIM listed Magnolia Petroleum Plc and privately owned Uplands Retail Limited which has a turnover of over £60m.
Non-Executive Directors
Mark William Smith, aged 63, Non-Executive Chairman
Mark has held several senior roles in creative and innovative communication businesses. He began his career as a chartered accountant at Touche Ross & Co. (Deloitte). He then spent 30 years at Chime Communications, which was acquired by Providence Private Equity in 2015.
Mark is currently chairman of Holiday Extras, a market leader in the provision of online ancillary travel services, a position which he has held for 15 years. He is also a non-executive director at The Dods Group, an AIM listed intelligence, media, training and events company, operating in over 50 countries.
Christopher Paul Sweetland, aged 63, Non-Executive Director
Chris qualified as a chartered accountant with KPMG before spending 9 years overseas in a variety of financial roles with PepsiCo Inc. In 1989, when he was CFO for the Central Europe Beverages Division, he was recruited by WPP to be part of their small central team. Chris retired from his role as WPP Deputy Group Finance Director in 2016 having spent 27 years helping build the company and having been involved in all aspects of operations, investor relations and the many acquisitions that built that group. Chris also represented WPP on the boards of a number of companies both in the UK and overseas.
Isabel Jane Kelly, aged 52, Non-Executive Director
Isabel is the founder of Profit with Purpose, a social purpose consultancy working with companies and non-profits. She is also a 'Resident Expert' at the Skoll Centre, Said Business School, Oxford University, where she is researching the organisational structures used by businesses to deliver social impact. In 2002 Marc Benioff, CEO of Salesforce.com, hired Isabel to establish the Salesforce Foundation internationally (now Salesforce.org). For 12 years she grew and led an international team delivering technology, grants and programmes in 110 countries, as well as generating revenue of $12m to fund the work. Isabel worked at Oxfam and Amnesty International for 12 years prior to joining Salesforce.
This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.
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