

Announcements.

Looking to discover a little more about our client companies?
A selection of news and recent announcements can be found here.
Xeros Tech Grp plc : Xeros expands geographic footprint
RNS Number : 0774X Xeros Technology Group plc 26 August 2015 26 August 2015 Xeros Technology Group plc Xeros expands partnership agreements, entering Canadian, Caribbean and Latin American commercial laundry and dry cleaning markets Xeros Technology Group plc (AIM: XSG, "Xeros") the innovative developer of a……
RNS Number : 0774X
Xeros Technology Group plc
26 August 2015
26 August 2015
Xeros Technology Group plc
Xeros expands partnership agreements, entering Canadian, Caribbean and Latin American commercial laundry and dry cleaning markets
Xeros Technology Group plc (AIM: XSG, "Xeros") the innovative developer of a patented polymer bead cleaning system with multiple identified commercial applications, announces that it has expanded its Commercial Laundry footprint into Canada, the Caribbean and Latin America, demonstrating growing acceptance of and demand for Xeros' polymer bead cleaning technology beyond the US Commercial Laundry market.
In Canada, Xeros has entered into a Forward Channel Partner agreement with Michael St. Clair Fine Cleaners, a dry cleaning and laundry specialist, under which Xeros' polymer bead laundry systems will be sold and serviced. Michael St. Clair services much of Vancouver's hospitality industry and has retail locations across the city.
This partnership will help bring Xeros' patented cleaning technology to the Canadian market, a country in which changing climate conditions and increased energy demand has given rise to nationwide initiatives to accelerate utility conservation efforts.
Xeros has also entered into a Forward Channel Partner agreement with Worldwide Laundry, Inc., a full service laundry equipment, parts and supplies company, to sell and service Xeros' polymer bead cleaning laundry systems. Worldwide Laundry, Inc. will be facilitating the delivery of Xeros cleaning solutions to the broader Caribbean and Latin American markets, both of which offer significant drivers for growth as severe drought conditions and rising energy prices are increasing demand for ecologically sustainable but commercially viable solutions.
The Caribbean islands are some of the most vulnerable countries in the world to water shortages. The impact of climate change is expected to raise the sea level significantly, increase salt-water intrusion, flooding and hurricanes, and decrease rainfall. Today, the islands are experiencing the worst drought conditions in five years. Puerto Rico, St. Lucia, and Cuba are all suffering drought and have implemented water conservation restrictions. In addition, according to Caribbean Development Bank (CDB), Caribbean electricity costs are approximately four times the average rate in North America.
Xeros Chief Executive Officer, Bill Westwater, commented:
"We are hugely encouraged by Xeros' expansion internationally, further evidencing the relevance and increasing acceptance of Xeros' near-waterless and energy-saving cleaning solution in geographic markets that can no longer ignore issues around water scarcity and need for energy conservation.
"These agreements also demonstrate the success of our Forward Channel Partners programme, in which we create a broad sales and service network across the Americas of established laundry industry players.
"In a world that can no longer depend on traditional aqueous processes, Xeros offers unprecedented performance and value for customers."
For further information, please contact:
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Xeros Technology Group plc www.xeroscleaning.com |
Via Instinctif Partners |
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Bill Westwater, Chief Executive Officer Chris Hanson, Finance Director |
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Jefferies International (Nominated Adviser) |
Tel: 020 7029 8000 |
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Simon Hardy / Harry Nicholas |
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Instinctif Partners |
Tel: 020 7457 2020 |
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Helen Tarbet / James Gray |
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This information is provided by RNS
The company news service from the London Stock Exchange
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CloseNeville Registrars welcomes Acorn Minerals plc
Neville Registrars are delighted to welcome Acorn Minerals plc as the newest addtion to its list of client companies. Acorn Minerals plc pursues investment opportunities in the mining, minerals & energy sectors. Further information can be found on the Company's website: http://www.acornminerals.com/…
Neville Registrars are delighted to welcome Acorn Minerals plc as the newest addtion to its list of client companies.
Acorn Minerals plc pursues investment opportunities in the mining, minerals & energy sectors. Further information can be found on the Company's website: http://www.acornminerals.com/
CloseAvanti Comms Group : Completion of HYLAS 4 satellite financing
RNS Number : 3194W Avanti Communications Group Plc 18 August 2015 18 August 2015 AVANTI COMMUNICATIONS GROUP PLC Completion of HYLAS 4 satellite financing Avanti Communications Group plc ("Avanti"), a leading provider of satellite data communications services in Europe, the Middle East and Africa ("EMEA"), announces……
RNS Number : 3194W
Avanti Communications Group Plc
18 August 2015
18 August 2015
AVANTI COMMUNICATIONS GROUP PLC
Completion of HYLAS 4 satellite financing
Avanti Communications Group plc ("Avanti"), a leading provider of satellite data communications services in Europe, the Middle East and Africa ("EMEA"), announces the completion of financing for its HYLAS 4 satellite, in line with the previously announced financing plan.
Avanti has successfully placed $125m in Senior Secured Notes due 2019 (the "Notes") under the Company's existing indenture. The Notes will be issued at a small discount to the current trading price of Avanti's existing notes and will have a coupon of 10%.
The investor group was led and managed by MAST Capital Management, LLC, a Boston-based investment firm.
HYLAS 4 remains on-track for launch in early 2017 and will complete Avanti's coverage of EMEA. The majority of the satellite's capacity will serve high-growth markets in Africa. The Company expects that this will consolidate its first mover advantage across EMEA, and enhance the future cash generation potential of the Group.
In addition, Avanti has also simultaneously conducted an equity capital raising (the "Capital Raising"). Avanti has issued 3,592,781 new ordinary shares (the "New Ordinary Shares") of 1p each ("Ordinary Shares") at a price of 200.65p per New Ordinary Share, to raise approximately £7.2m ($11.3m) (net of expenses) in order to satisfy demand from bond investors.
The Capital Raising has been conducted under the Company's existing shareholder authorities to allot new Ordinary Shares for cash on a non-pre-emptive basis. The issue price of 200.65p represents a discount of 4.0% to the closing middle market price of 209.00p per existing Ordinary Share on 17 August 2015, the last dealing day prior to this announcement.
Application has been made to the London Stock Exchange for the New Ordinary Shares to be admitted to trading on AIM ("Admission"). The New Ordinary Shares will represent approximately 2.47% of Avanti's issued Ordinary Share capital immediately following Admission. It is expected that Admission will become effective and that dealings in the New Ordinary Shares will commence on AIM at 8.00 a.m. on 21 August 2015. The Notes will be issued on the same day.
Following the Admission, the total number of Ordinary Shares with voting rights admitted to trading on AIM will be 145,396,350. The New Ordinary Shares will rank pari passu in all respects with Avanti's existing Ordinary Shares in issue. Avanti does not hold any Ordinary Shares in treasury.
The above figure of 145,396,350 Ordinary Shares may be used by shareholders in Avanti as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the share capital of Avanti, under the Financial Conduct Authority's Disclosure and Transparency Rules.
Peter Reed, Partner and Portfolio Manager, MAST Capital Management, LLC said: "We have long admired Avanti's business and its management team. The completion of the financing for the HYLAS 4 satellite is an exciting and important milestone for the Company and we are pleased to play a leadership role in the satellite's development by investing $125 million into newly issued notes and shares."
David Williams, Avanti Chief Executive, said, "Today's funding for HYLAS 4 enables us to complete our coverage of EMEA in early 2017. Avanti now offers more High Throughput Satellite capacity to its telco customers in Africa than any other satellite operator, enabling us to build strong partnerships for the long term. Millions of people and businesses in Africa don't have to wait for tomorrow, Avanti delivers superfast broadband today."
For further information please contact:
Avanti: Matthew Springett, +44 (0)207 749 6703
Montfort: Nick Miles / James Olley, +44 (0)203 770 7909
Cenkos Securities: Max Hartley (Nomad) / Julian Morse, +44 (0)207 397 8900
Redleaf: Hannah Nicolas, +44 (0)207 382 4734
MAST: Steve Bruce or Taylor Ingraham, ASC Advisors, +1 203 992 1230
Notes to editors
Avanti connects people wherever they are – in their homes, businesses, in government and on mobiles. Through the HYLAS satellite fleet and more than 150 partners in 118 countries, the network provides ubiquitous internet service to a quarter of the world's population. Avanti delivers the level of quality and flexibility that the most demanding telecoms customers in the world seek.
Avanti is the first mover in high throughput satellite data communications in EMEA. It has rights to orbital slots and Ka band spectrum in perpetuity that covers an end market of over 1.7bn people.
The Group has invested $1.2bn in a network that incorporates satellites, ground stations, datacentres and a fibre ring.
Avanti has a unique Cloud based customer interface that is protected by patented technology.
The Group has three satellites in orbit and a further two fully funded satellites under construction.
Avanti Communications is listed in London on AIM (AVN:LSE).
About MAST
Founded in 2002, MAST Capital Management, LLC is an SEC-registered investment advisor that specializes in event-driven and credit investments, focusing predominantly on middle market opportunities. Currently, MAST manages and sub-advises approximately $1.2bn for sophisticated institutional and family office investors globally. The Boston-based Firm is employee-owned with a minority stake held by Dyal Capital Partners, a subsidiary of Neuberger Berman.
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseSurrey County Cricket Club Bond Launched
Neville Registrars Limited is pleased to announce that the Surrey County Cricket Club Bond is now live. Anyone seeking further information on the bond or wishing to make an application should visit: https://www.surreycountycricketclubbond.com/…
Neville Registrars Limited is pleased to announce that the Surrey County Cricket Club Bond is now live.
Anyone seeking further information on the bond or wishing to make an application should visit:
https://www.surreycountycricketclubbond.com/
CloseEU Supply PLC : Contract Win
RNS Number : 1569W EU Supply PLC 17 August 2015 17 August 2015 EU Supply plc ("EU Supply", the "Company" or "the Group") Contract win EU Supply (LSE AIM: EUSP), the e-procurement software provider, is pleased to announce that it has been awarded a long term……
RNS Number : 1569W
EU Supply PLC
17 August 2015
17 August 2015
EU Supply plc
("EU Supply", the "Company" or "the Group")
Contract win
EU Supply (LSE AIM: EUSP), the e-procurement software provider, is pleased to announce that it has
been awarded a long term contract with Oslo Kommune (Capital City Council of Norway), in competition with several of its main competitors in Norway. The contract allows the city council central procurement and any of its subsidiaries the right to use the Company's CTMTM platform.
The contract is a 6 years fixed contract, with up to 2 years optional extensions, and is expected to lead to more than 50 organisational units and up to 800 users using the CTMTM platform by the time the new EU Directives are expected to become effective in Norway. Fees depend on the number of users of each module of the service. This is the third European capital city contract awarded to the Company in the last three months.
This agreement underpins the Company`s development in multiple markets and confirms management's confidence in growth for 2015 and beyond.
FURTHER ENQUIRIES
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Notes to Editors
EU Supply is the UK holding company of the EU Supply Group, a Sweden-based e-commerce business, which has an established, market-leading, multilingual e-procurement platform for e-sourcing, e-tendering and contract management, tailored for the highly regulated European public sector market.
Since 2006, the Group has invested heavily in employing specialist programmers to add functionality, legal compliance as required and security features to its Complete Tender Management™ ("CTM™") platform to ensure that the Group is ideally placed to secure new contracts with EU Member States and their Contracting Authorities. The platform is available in 16 different languages.
The Directors believe that the Group's CTM™ platform is one of the easiest to use and most functionally advanced solutions available in the market. The CTM™ platform is used by over 7,000 European public sector bodies in 10 EU/EEC Member States and has National Procurement System status in four Member States (the UK, Ireland, Norway and Lithuania).
The Company's shares were admitted to trading on AIM in November 2013 when the Company raised £5.0 million before expenses. In July 2014, the Company raised a further £1.35 million by way of a placing of new ordinary shares, the proceeds of which were mainly used to strengthen the Company's balance sheet, provide working capital to support the growth of the business as it expands and aims to gain market share and to provide additional funds for sales and marketing.
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseNetcall PLC : Contract Win
RNS Number : 1404W Netcall PLC 17 August 2015 17 August 2015 RNS Reach Netcall plc ("Netcall" or the "Company") Contract Win Largest SaaS contract for new Liberty platform Netcall plc (AIM: NET), a leading customer engagement software provider, is pleased to announce that it has secured a……
RNS Number : 1404W
Netcall PLC
17 August 2015
17 August 2015
RNS Reach
Netcall plc
("Netcall" or the "Company")
Contract Win
Largest SaaS contract for new Liberty platform
Netcall plc (AIM: NET), a leading customer engagement software provider, is pleased to announce that it has secured a five-year SaaS contract worth a minimum of £1.4 million to provide its Liberty multi-channel contact centre and unified communication solutions.
As part of the agreement Netcall will deliver a range of inbound and outbound voice, email and chat applications that utilise Liberty's business process management capabilities for workflow automation and data integration with legacy systems. This will enable the client to deliver a consistent, personalised customer experience and achieve efficiencies. Netcall's solution will replace a number of legacy on-premise systems with a hosted solution that provides a virtual contact centre for the client's six sites.
Henrik Bang, CEO of Netcall commented: "Today's announcement represents a milestone for Netcall as it is the largest SaaS contract we have been awarded for our new Liberty platform.
"The end-to-end, fully hosted solution will transform the way in which our client interacts with its customers and we look forward to working with them."
For further enquiries, please contact:
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Netcall plc |
Tel. +44 (0) 330 333 6100 |
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Henrik Bang, CEO Michael Jackson, Chairman James Ormondroyd, Group Finance Director |
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finnCap Limited (Nominated Adviser and Broker) |
Tel. +44 (0) 20 7220 0500 |
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Stuart Andrews / James Thompson, Corporate Finance |
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Simon Johnson, Corporate Broking |
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Alma PR |
Tel. +44 (0) 7780 901979 |
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Josh Royston / Hilary Buchanan |
+44 (0) 7515 805218 |
About Netcall plc
Netcall is a UK company quoted on the AIM market of the London Stock Exchange. Netcall's software product suite provides compelling business process solutions for end-to-end customer engagement, incorporating multi-channel contact centre, workforce optimisation, business process management and enterprise content management. The Netcall software platform helps organisations meet the growing demands of their customers and prospects whilst improving internal efficiencies, thereby increasing profitability and customer satisfaction.
Netcall's customer base contains over 700 organisations in both the private and public sectors. These include two thirds of NHS Acute Health Trusts, major telecoms operators such as BT and leading organisations including Interflora, Lloyds Banking Group, Cineworld, Interserve, Prudential, British Sugar and Thames Water.
For further information, please consult the Netcall website: www.netcall.com
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseTransense Technlgy : New Translogik iTrack Contract Win
RNS Number : 9085V Transense Technologies PLC 13 August 2015 13th August 2015 Transense Technologies plc ("Transense" or the "Company") New Translogik iTrack Contract Win in Australia Transense Technologies plc (AIM: TRT), the provider of sensor systems for the transportation and industrial markets, is pleased to announce……
RNS Number : 9085V
Transense Technologies PLC
13 August 2015
13th August 2015
Transense Technologies plc
("Transense" or the "Company")
New Translogik iTrack Contract Win in Australia
Transense Technologies plc (AIM: TRT), the provider of sensor systems for the transportation and industrial markets, is pleased to announce that its trading division, Translogik, has won another contract through its Australian partner, Brownfield Engineering & Maintenance PTY LTD ("Brownfield").
The agreement is to supply 47 iTrack mining tyre monitoring systems for large haul trucks to the Saraji coal mine in the Bowen Basin, Queensland, owned by the BHP Billiton Mitsubishi Alliance (BMA). The contract includes the sale of equipment on a finance lease. In addition to the sale there will be income from service and rental for a minimum period of two years.
Graham Storey, CEO of Transense said "This is another significant contract win for Translogik's iTrack system in quick succession, after other recent wins with Glencore in Australia, and BHP in Chile. The new strategy of offering a range of payment methods, including rental and finance lease, appears to have eased the barrier to large-scale adoption within the mining industry and we look forward to further agreements in due course. "
Darryl Crowder, Managing Director of Brownfield said "The important role of tyre monitoring as part of a total safety and performance monitoring strategy within the mining sector is an increasingly major focus in Australia. We have received significant interest in the iTrack system due to its accuracy and ease of use compared to competing systems, and I am confident that this high level of enquiries will translate into further uptake."
For further information, please contact:
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Transense Technologies plc Graham Storey, Chief Executive
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Tel: +44 1869 238 380 |
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finnCap Ed Frisby, Giles Rolls (Corporate Finance) Tony Quirke, Alice Lane (Corporate Broking)
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Tel: +44 20 7220 0500 |
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IFC Advisory Tim Metcalfe, Graham Herring, Heather Armstrong |
Tel: +44 20 3053 8671 |
About Transense Technologies
Based in Oxfordshire, UK, Transense has developed patent-protected sensor systems and supporting technology for use in a variety of diverse high growth markets. Transense's Surface Acoustic Wave (SAW) wireless, battery-less, sensor systems offer significant advantages over legacy wireless sensor systems. Transense is targeting the global electrical Smart Grid applications market, the transport and mining industries, and the global torque, temperature and pressure sensing markets, via its three trading divisions, IntelliSAW, Translogik and SAWSense, respectively.
Transense's shares are admitted to trading on AIM, a market operated by the London Stock Exchange (AIM: "TRT").
About Translogik
Translogik, a trading division of Transense Technologies plc, is a provider of innovative tyre management solutions for the OTR (Off-the-Road), commercial and passenger vehicle markets.
The product portfolio includes wireless tyre temperature & pressure monitoring systems, tread depth, pressure and temperature data collection tools for truck, bus and OTR vehicle tyre inspections, and RFID (Radio Frequency Identification) tags, patches and UHF readers for tyres and general asset tracking.
The Products have been designed to operate in the most hostile and demanding environments, such as mining, earth-moving and construction.
About iTrack
Translogik's iTrack system provides a rugged and reliable solution with a range of features that allows mine operators to track their vehicle's tyre temperature and pressure, speed, braking and location in real-time and receive early warning of potential problems or hazards.
The availability of live tyre and vehicle data allows swift remedial action to be taken, which can be the difference between safe mine operation and a major incident. By ensuring the vehicle's tyres are operating within recommended temperature and pressure limits, iTrack brings increased levels of safety to both the vehicle drivers and the technicians that work on them. In addition, the system allows for multiple concurrent geo-fence zones to be defined to ensure that vehicles are only operating in approved areas, further increasing the safety of the mine.
From a commercial perspective, by ensuring that tyres are correctly inflated and managed, tyre life is extended, fuel economy is improved and costly down-time from repairs and intervention is reduced, improving productivity. TKPH (Ton Kilometre Per Hour) calculations using loaded/unloaded weights and real-time route cycling allows tyres to be run at higher efficiency based on their TKPH rating (based on size, construction type, rubber compound and hours usage) without overheating or causing premature deterioration.
Alarms trigger when user configurable operational threshold levels, such as tyre temperature, are exceeded, providing early warning of potential tyre or vehicle failure.
About Brownfield Engineering and Maintenance PTY LTD
Brownfield provides maintenance and operational support to major mining companies. With three facilities strategically positioned in the Bowen Basin, Hunter Valley & Perth – Australia's premier mining locations.
Brownfield was formed with a focus on supporting the working assets of the mining sector and has been integrated into three key services offerings:
· Products: mining and associated products
· Engineering: engineering services to the mining industry
· Maintenance: mining maintenance services
http://www.brownfield.com.au/home/
About Saraji Mine
The Saraji Coal Mine is a coal mine located near Dysart in the Central Queensland region of Australia. The mine has coal reserves amounting to 648 million tonnes of coking coal, one of the largest coal reserves in the world. The mine has an annual production capacity of 5 million tonnes of coal. It is located in the Bowen Basin an area with significant coal deposits and numerous mines.
Saraji mine utilises open-cast extraction methods. It is owned by the BHP Billiton/Mitsubishi Alliance (BMA). The mine has a total of 11 coal seams.
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseNetplay TV PLC : Acquisition of Digital Marketing Business
RNS Number : 7648V Netplay TV PLC 12 August 2015 Date: 12 August 2015 On behalf of: NetPlay TV plc ('the Company') along with its subsidiaries (the 'Group' or 'NetPlay' or 'NetPlay TV') Embargoed until: 0700hrs NetPlay TV plc Acquisition of Digital Marketing Business NetPlay……
RNS Number : 7648V
Netplay TV PLC
12 August 2015
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Date: |
12 August 2015 |
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On behalf of: |
NetPlay TV plc ('the Company') along with its subsidiaries (the 'Group' or 'NetPlay' or 'NetPlay TV') |
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Embargoed until: 0700hrs |
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NetPlay TV plc
Acquisition of Digital Marketing Business
NetPlay TV (AIM: NPT), the interactive gaming company, is pleased to announce the acquisition of Otherside Inc. ("Otherside"), an online marketing, product development and technology company, for a total consideration of £3.2m (the "Acquisition").
Strategic rationale for the Acquisition
The Board has been actively looking at the market and considering various options as part of its stated strategy to expand the business both organically and through M&A. The Board believes the acquisition of Otherside will provide NetPlay with a number of key benefits, including;
· A robust media platform and specialist staff enabling the Group to control and tailor its digital marketing strategies.
· Synergies within the Group's existing gaming operations, delivering additional traffic to the Group's existing brands as well as a marketing skillset complimentary to its core products.
· The diversification of NetPlay's revenue by maintaining Otherside's current revenue streams and growing this business by building on the success of the marketing company to date.
Information on Otherside
Founded in 2008, Otherside specialises in online marketing, display media and affiliation, underpinned by its proprietary online marketing platform across a range of sectors. Otherside generated revenues of £2.6m, Adjusted EBITDA* of £0.6m and profit before tax of £0.4m in its unaudited financial information for the financial year ended 31 May 2015. This transaction constitutes a substantial transaction under the AIM Rules.
Terms of the Acquisition
The consideration for the Acquisition, for the trade and assets of Otherside, comprises an initial consideration of £2.7 million, to be satisfied by a cash payment from the Group's existing cash resources. Further consideration of £0.5 million is payable over 12 months from date of completion subject to the vendor completing certain deliverables as well as the continued employment of certain key individuals.
Bjarke Larsen, Chief Executive Officer of NetPlay TV commented:
"I am delighted to announce the acquisition of Otherside, which will strategically align with our core business and support our digital strategy across the Group's brand portfolio. As previously stated, NetPlay is in a strong position to pursue appropriate, value-enhancing M&A activity and we are confident that this acquisition further strengthens the Group's digital reach. We look forward to integrating this specialist team into our operations and capitalising on the numerous commercial and margin-enhancing opportunities presented by the acquisition."
Enquiries:
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NetPlay TV plc |
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Bjarke Larsen, Chief Executive Officer Akshay Kumar, Group Finance Director
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Via Redleaf |
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Redleaf Communications |
Tel: 020 7382 4730 |
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Rebecca Sanders-Hewett Susie Hudson
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Shore Capital (Nominated Adviser and Broker) |
Tel: 020 7408 4090 |
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Stephane Auton Edward Mansfield
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Notes to Editors:
About NetPlay TV plc
NetPlay TV plc is admitted to trading on the AIM market of the London Stock Exchange (NPT). The Group operates a number of interactive gaming services under a UK remote operating license and Alderney gaming license, including SuperCasino.com, Jackpot247.com and Vernons.com. Its TV services can also be viewed 24 hours a day live on Sky Channel 862, and every evening on ITV and Channel 5.
The Company is focused on the delivery of a converged interactive gaming experience allowing its players to interact with its games on a variety of platforms, TV, internet, mobile and tablet from a common integrated wallet.
About OtherSide Inc.
OtherSide Inc. is a team of marketing experts, creative people, programmers and business professionals whose main goal is to create, implement and uphold new and better ideas to market products and services in the Internet.
Founded in 2008, OtherSide Inc. has committed to the newest, most advanced and best performing solutions for online marketing in order to maximize exposure, revenues and optimize campaigns for best ROI.
OtherSide Inc. specializes in all the phases of the online marketing, including product development, site and funnel building, infrastructure and technology, design, creativity, media buying and optimisation, and customer service.
[*] Adjusted EBITDA is non-GAAP company specific measure
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseOxford Pharmascience : Preliminary PK Data & Initiation of Further Study
RNS Number : 7988V Oxford Pharmascience Group PLC 12 August 2015 Oxford Pharmascience Group plc ("Oxford Pharmascience" or the "Company") Preliminary Pharmacokinetic Data and Initiation of Pilot Clinical Study to Demonstrate Improved GI Profile for OXPzero™ Ibuprofen Oxford Pharmascience Group Plc (AIM: OXP), the specialty pharmaceutical company that……
RNS Number : 7988V
Oxford Pharmascience Group PLC
12 August 2015
Oxford Pharmascience Group plc
("Oxford Pharmascience" or the "Company")
Preliminary Pharmacokinetic Data and
Initiation of Pilot Clinical Study
to Demonstrate Improved GI Profile for OXPzero™ Ibuprofen
Oxford Pharmascience Group Plc (AIM: OXP), the specialty pharmaceutical company that redevelops medicines to make them better, safer and easier to take, today announces that preliminary pharmacokinetic (PK) data confirms that OXP001(2) has successfully met its optimisation objectives for immediate release and complete drug absorption. The Company has commenced dosing in the second phase of the study, which seeks to prove the reduced gastro-intestinal (GI) irritation benefit of OXPzero™ Ibuprofen by endoscopic evaluation.
The randomized pilot PK study was a single-dose, two-arm UK study comparing the OXP001(2) 400mg chewable OXPzero™ Ibuprofen tablet and the reference Brufen® 400mg tablet (ibuprofen), in ten subjects. Preliminary PK data show comparable AUC (Area Under the Curve or total drug exposure over time) and tmax (time to reach maximum serum concentration) results, demonstrating that OXP001(2) is now a product with immediate and complete drug release characteristics. While the PK profile of the product appears to be similar to that of Brufen® on these measures, the maximum level of drug concentration in plasma (Cmax) appears to be lower compared to Brufen® but remains well within the range which the drug has therapeutic effect. The Company believes this preliminary PK data represents an acceptable clinical profile suitable for commercialisation. Additional PK data will be collected during the next phase of the study.
The taste masked benefit of OXPzero™ Ibuprofen was also assessed via subject interviews, during the first phase of this study, with consistent feedback confirming that the chewable tablets were tasteless, with none of the burn or after-taste issues associated with standard ibuprofen.
Following analysis of the preliminary PK data, the Company is proceeding to the second phase of the study, which aims to demonstrate a significantly reduced GI side effect profile compared to standard 400mg Brufen® tablets. The product to be tested, OXP001(2), is a 400mg chewable, taste masked, oral formulation of ibuprofen.
This phase of the study is a randomised, assessor-blinded, controlled pilot clinical study to assess the severity of upper GI damage via endoscopic assessment following 7 days' treatment of 2.4g/day of ibuprofen dosed as either OXP001(2) or Brufen®. A prior study in 2014 demonstrated significant GI side-effect benefits, compared to Brufen®, using an early version of OXP001 for which the PK profile has since been optimised for immediate release and complete drug absorption. Headline results on the second phase are expected to be released in Q4 2015, along with complete PK data and further taste masking assessments.
Marcelo Bravo, Chief Executive Officer, commented:
"We are pleased to confirm that OXP001(2) now achieves immediate release and complete drug absorption in vivo and that the taste masking benefit of the technology has been validated. We are confident the product is achieving release properties in line with the objective of delivering a reduction in GI irritation. Demonstrating that OXP001(2) achieves a significant reduction in GI erosions compared to Brufen® in this new formulation will validate OXPzero™ Ibuprofen as a disruptive compound in the major $4bn ibuprofen market."
Further details about the study can be found at www.ClinicalTrials.gov.
For further information:
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Oxford Pharmascience Group Plc |
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Marcelo Bravo, Chief Executive |
+44 20 7 554 5875 |
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N+1 Singer (Nominated Adviser & Broker) |
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Aubrey Powell/Jen Boorer |
+44 20 7496 3000 |
About Oxford Pharmascience Group Plc
Oxford Pharmascience Group Plc uses a range of proprietary technology platforms to re-develop existing medicines to make them better, safer or easier to take. The Company does not manufacture or sell its own pharmaceutical products direct to consumers but instead seeks to license its technologies and dossiers to a network of partners, mainly leading pharmaceutical companies with Rx (prescription) and OTC (Over the Counter) branded portfolios.
Oxford Pharmascience Group Plc focuses on existing medicines that are proven to be safe and effective but nevertheless still have associated issues and side effects often affecting compliance. By working with such medicines the Company is able to develop new innovative products for a fraction of the cost, in much quicker timescales and without the high risk of failure associated with developing new drugs.
This information is provided by RNS
The company news service from the London Stock Exchange
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CloseObtala Resources Ltd : Farm Certification: Tanzania
RNS Number : 6394U Obtala Resources Limited 31 July 2015 31 July 2015 Obtala Resources Limited ("Obtala" or the "Company") (AIM: OBT) Farm Certification: Tanzania Obtala Resources Limited (AIM:OBT), the vertically integrated agribusiness, timber and retail company, is pleased to announce that it has be……
RNS Number : 6394U
Obtala Resources Limited
31 July 2015
31 July 2015
Obtala Resources Limited
("Obtala" or the "Company")
(AIM: OBT)
Farm Certification: Tanzania
Obtala Resources Limited (AIM:OBT), the vertically integrated agribusiness, timber and retail company, is pleased to announce that it has be awarded the internationally recognized farm GLOBALG.A.P. certification for its agricultural operations in Tanzania.
The Company has received notification from our consultants that the GLOBALG.A.P. Certification has been awarded to our farming operation in Tanzania. This is a significant milestone for the Company and overcomes a barrier to entry with many international food groups.
GLOBALG.A.P. is the internationally recognized standard for farm production. The core product standard is the result of years of intensive research and collaboration with industry experts, producers and retailers around the globe. The goal is safe and sustainable agricultural production to benefit farmers, retailers and consumers throughout the world.
GLOBALG.A.P. Certification covers:
· Food safety and traceability
· Environment (including biodiversity)
· Workers' health, safety and welfare
· Animal welfare
· Includes;
o Integrated Crop Management (ICM),
o Integrated Pest Control (IPC),
o Quality Management System (QMS), and
o Hazard Analysis and Critical Control Points (HACCP)
GLOBALG.A.P. demands, among other things, greater efficiency in production. It improves business performance and reduces waste of vital resources. It also requires a general approach to farming that builds in best practices for generations to come.
We continue to address additional requirements to secure BRC Global Standards Certification for the processing unit, which will allow us to export internationally to food producers, wholesalers and retailers. An audit inspection was conducted in late June and a certification audit is expected in October 2015.
Commenting on today's announcement, Francesco Scolaro, Chairman of Obtala, said: "As a Board we are very pleased to have gained the GLOBALG.A.P. certification. The award is the result of much hard work and time ensuring full compliance with required international food safety standards. I personally want to thank the team on the ground for their efforts as we can now access new market opportunities for our projects, which will have a positive impact on the Company and importantly the local community in Tanzania. We are working towards BRC Global Standards Certification on the processing unit and hope to have the certification audit in October. The award of these certificates, coupled with the Export Processing Zone ("EPZ") Award, received in late 2014, will greatly enhance market opportunities for the farm and processing unit, in a highly attractive business sector which is expected to continue experiencing strong growth. I look forward to updating shareholders in due course."
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Obtala Resources Francesco Scolaro – Chairman
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+44 (0)20 7099 1940
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ZAI Corporate Finance Limited (Nomad) |
+44 (0)20 7060 2220 |
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Ray Zimmerman Richard Morrison |
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Brandon Hill Capital (Broker) |
+44 (0)20 3463 5000 |
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Jonathan Evans |
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Square 1 Consulting (Public Relations) |
+44 (0)20 7929 5599 |
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David Bick Mark Longson |
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Other information:
GLOBALG.A.P.
"Putting Food Safety and Sustainability on the Map"
G.A.P. stands for Good Agricultural Practice – and GLOBALG.A.P. is the worldwide standard that assures it.
GLOBALG.A.P. is a global organization with a crucial objective: safe, sustainable agriculture worldwide. GLOBALG.A.P. sets voluntary standards for the certification of agricultural products around the globe-and more and more producers, suppliers and buyers are harmonizing their certification standards to match.
The purpose of GLOBALG.A.P. is to create private sector incentives for agricultural producers worldwide to adopt safe and sustainable practices to make this world a better place to live in for our children. Globally connecting farmers and brand owners in the production and marketing of safe food to provide reassurance for consumers. GLOBALG.A.P. lays the foundation for the protection of scarce resources by the implementation of Good Agricultural Practices with a promise for a sustainable future.
BRC Global Standards
http://www.brcglobalstandards.com/
BRC Global Standards is a leading safety and quality certification programme, used by over 22,000 certificated suppliers in 123 countries, with certification issued through a worldwide network of accredited certification bodies.
The Standards guarantee the standardisation of quality, safety and operational criteria and ensure that manufacturers fulfil their legal obligations and provide protection for the end consumer. BRC Global Standards are now often a fundamental requirement of leading retailers.
This information is provided by RNS
The company news service from the London Stock Exchange
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